Anti-FBXW11 aptamer SELEX Service(Cat#: CTApt-1858)
This is an aptamer development services to screening aptamers binds to the FBXW11 with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
FBXW11 |
| Alternative Names |
F-Box And WD Repeat Domain Containing 11; BTRCP2; F-Box And WD Repeats Protein Beta-TrCP2; F-Box/WD Repeat-Containing Protein 11; F-Box/WD Repeat-Containing Protein 1B; F-Box And WD-40 Domain Protein 1B; F-Box And WD-40 Domain Protein 11; Homologous To Slimb Protein; KIAA0696; FBXW1B; BTRC2; FBW1B; Fbw11; Hos; Beta-Transducin Repeat-Containing Protein 2; F-Box Protein Fbw1b; NEDJED; FBXW11; Fbw1b; HOS |
| Gene ID |
23291 |
| UniProt ID |
Q9UKB1 |
| Target Overview |
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
