Anti-FGF2 Aptamer SELEX Service(Cat#: CTApt-756)

This is an aptamer development services to screening aptamers binds to the FGF2 with an affinity of 1nM~1μM.

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Lot Number

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Summary
Specifications
Target Category Protein
Target FGF2
Alternative Names BFGF; FGFB; FGF-2; HBGF-2
Gene ID 2247
UniProt ID P09038
Target Overview The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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