This product is an aptamer which binds to the HIV-1 Integrase with an affinity of <20 nM.
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| Target Category | Protein |
| Target | HIV-1 Integrase |
| Chemical Modification | RNA |
| Length | 60-80 nt |
| Affinity (Kd) | <20 nM |
| Binding Conditions/Buffer | Buffer A (50 mM HEPES, 1 mM DTT, 1 mM APMSF) Binding Buffer (50 mM Na-HEPES (pH 7.5), 250 mM NaCl, 2 mM DTT, 10 mM MnCl2, 5 mM CHAPS) |
| GC Content | 54.55 |
| Molecular Weight | 24933.1 g/mole |
| Extinction Coefficient | 767300 L/(mole·cm) |
| nmoles/OD260 | 1.3 |
Using the anti-HIV-1 Integrase aptamer significantly enhanced the quality of my researchExcellentThe aptamer's robust performance and ease of use made it an excellent choice for my experiments. I am extremely satisfied with this aptamer.
Facilitating my studies on HIV replication and integrationExcellentIt played a crucial role in my research, allowing me to evaluate the impact of various compounds on integrase activity.
User-friendly protocol and consistent performanceExcellentI am impressed with the anti-HIV-1 Integrase aptamer's ability to target the integrase protein with high specificity. The aptamer's user-friendly protocol and consistent performance made my experiments more manageable and yielded reliable data.