Anti-Human CD63 Aptamer(Cat#: CTMM-0124-LH38)
This product is an aptamer which binds to Human CD63 domain with an affinity of 1-50 nM.
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Summary
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Specifications
| Target Category |
Protein |
| Target |
CD63 |
| Alternative Names |
CD63 Molecule; TSPAN30; ME491; MLA1; Ocular Melanoma-Associated Antigen; CD63 Antigen (Melanoma 1 Antigen); Melanoma-Associated Antigen ME491; Tetraspanin-30; Granulophysin; CD63 Antigen; AD1 Antigen; Tspan-30; Pltgp40; HOP-26; OMA81H; Limp1; AD1; Lysosomal-Associated Membrane Protein 3; Lysosome Integral Membrane Protein 1; Melanoma-Associated Antigen MLA1; LAMP-3 |
| Gene ID |
967 |
| UniProt ID |
P08962 |
| Target Overview |
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. |
| Type |
DNA |
| Species Reactivity |
Human |
| Length |
<50 nt |
| Affinity (Kd) |
1-50 nM |
| Binding Conditions/Buffer |
PBS with 2.0 mM MgCl2, 0.02% Tween 20, and 100 µg/mL Salmon Sperm DNA, pH=7.4 |
| GC Content |
57.14% |
| Molecular Weight |
12356.1 g/mole |
| nmoles/OD260 |
2.293 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
