This product is an aptamer which binds to human CD70 with an affinity of <100 nM.
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| Target Category | Protein |
| Target | CD70 |
| Alternative Names | Cluster of Differentiation 70; CD70 Molecule; LPFS3; Surface Antigen CD70 |
| Gene ID | 970 |
| UniProt ID | P32970 |
| Target Overview | CD70 is a costimulatory molecule expressed on activated immune cells and certain cancers, making it a promising target for immunotherapy in oncology. |
| Type | DNA |
| Species Reactivity | Human |
| Length | 60-80 nt |
| Affinity (Kd) | < 100 nM |
| Binding Conditions/Buffer | 50 mmol/L K₂HPO₄, 150 mmol/L NaCl, 0.05% Tween 20, BSA 1 μg/mL, 0.1 mg/mL yeast tRNA, pH 7.5 |
| GC Content | 0.625 |
| Molecular Weight | 25037.23 g/mole |
| Extinction Coefficient | 779800 L/(mole·cm) |
| nmoles/OD260 | 1.28238 |