Anti-Human GH1 Aptamer(Cat#: CTWZ-0124-WZ29)

This product is an aptamer which binds to human GH1 with an affinity of 200-1000 nM.

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Summary

Specifications
Target Category Protein
Target GH1
Alternative Names Growth Hormone 1; GH-N; GH; Pituitary Growth Hormone; Somatotropin; HGH-N; GHN; Growth Hormone B5; Growth Hormone; IGHD1A; IGHD1B; IGHD2; GHB5
Gene ID 2688
UniProt ID P01241
Target Overview The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature.
Type DNA
Species Reactivity Human
Length 50-100 nt
Affinity (Kd) 200-1000 nM
GC Content 45.45%
Molecular Weight 16389.7 g/mole
nmoles/OD260 1.696
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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