This product is an aptamer which binds to human IGFIIR with an affinity of <50 nM.
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
| Target Category | Protein |
| Target | IGFIIR |
| Alternative Names | Insulin Like Growth Factor II Receptor |
| Target Overview | IGFIIR (Insulin-like Growth Factor II Receptor) regulates cell growth and survival by mediating IGF-II signaling, and its dysregulation is linked to cancer progression. |
| Type | DNA |
| Species Reactivity | Human |
| Length | 60-80 nt |
| Affinity (Kd) | < 50 nM |
| Binding Conditions/Buffer | PBS containing 0.05% Tween 20 and 20 mM Tris, 500 mM imidazole, pH 7.5 |
| GC Content | 0.4868 |
| Molecular Weight | 23611.4 g/mole |
| Extinction Coefficient | 754800 L/(mole·cm) |
| nmoles/OD260 | 1.32485 |