This product is an aptamer which binds to human IL2Rα with an affinity of <20 nM.
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| Target Category | Protein |
| Target | IL2Rα |
| Alternative Names | Interleukin 2 Receptor Alpha; CD25; Interleukin 2 Receptor Subunit Alpha; CD25 Antigen |
| Gene ID | 3559 |
| UniProt ID | P01589 |
| Target Overview | IL2Rα (Interleukin-2 Receptor Alpha) is a subunit of the IL-2 receptor complex, critical for T-cell activation and proliferation, and is targeted in autoimmune disease therapies. |
| Type | DNA |
| Species Reactivity | Human |
| Length | 60-80 nt |
| Affinity (Kd) | < 20 nM |
| Binding Conditions/Buffer | 50 mM K₂HPO₄, pH 7.5 with 150 mM NaCl, 0.05% Tween 20, BSA 1 μg/ml, 0.1 mg/ml yeast tRNA |
| GC Content | 0.6 |
| Molecular Weight | 24884.11 g/mole |
| Extinction Coefficient | 743200 L/(mole·cm) |
| nmoles/OD260 | 1.34553 |