Anti-Human IL2Rα Aptamer(Cat#: CTMM-0726-JL78)

This product is an aptamer which binds to human IL2Rα with an affinity of <20 nM.

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Lot Number

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Summary
Specifications
Target Category Protein
Target IL2Rα
Alternative Names Interleukin 2 Receptor Alpha; CD25; Interleukin 2 Receptor Subunit Alpha; CD25 Antigen
Gene ID 3559
UniProt ID P01589
Target Overview IL2Rα (Interleukin-2 Receptor Alpha) is a subunit of the IL-2 receptor complex, critical for T-cell activation and proliferation, and is targeted in autoimmune disease therapies.
Type DNA
Species Reactivity Human
Length 60-80 nt
Affinity (Kd) < 20 nM
Binding Conditions/Buffer 50 mM K₂HPO₄, pH 7.5 with 150 mM NaCl, 0.05% Tween 20, BSA 1 μg/ml, 0.1 mg/ml yeast tRNA
GC Content 0.6
Molecular Weight 24884.11 g/mole
Extinction Coefficient 743200 L/(mole·cm)
nmoles/OD260 1.34553
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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