Anti-Human/Mouse CCL21 Aptamer(Cat#: CTMM-0124-TT20)
This product is an aptamer which binds to the Human/Mouse CCL21 with an affinity of 200-1000 pM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
CCL21 |
| Alternative Names |
C-C Motif Chemokine Ligand 21; SLC; 6Ckine; SCYA21; TCA4 2; ECL 2; Small Inducible Cytokine Subfamily A (Cys-Cys), Member 21; Efficient Chemoattractant For Lymphocytes; Secondary Lymphoid Tissue Chemokine; Chemokine (C-C Motif) Ligand 21; Beta Chemokine Exodus-2; C-C Motif Chemokine 21; CKb9; Secondary Lymphoid-Tissue Chemokine; Small-Inducible Cytokine A21; Beta-Chemokine Exodus-2; Exodus-2; EXODUS-2; 6CKINE; CKB9 |
| Gene ID |
6366 |
| UniProt ID |
O00585 |
| Target Overview |
This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19). |
| Type |
DNA |
| Species Reactivity |
Human; Mouse |
| Length |
50-100 nt |
| Affinity (Kd) |
200-1000 pM |
| Binding Conditions/Buffer |
150 mM NaCl, 2.7 mM KCl, 10 mM Na₂HPO₄, 2 mM KH₂PO₄, 1 mM MgCl₂, pH 7.4 |
| GC Content |
51.32% |
| Molecular Weight |
23781.51 g/mole |
| nmoles/OD260 |
1.38 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
