Anti-Human PDCD1 Aptamer(Cat#: CTMM-0124-LH36)

This product is an aptamer which binds to Human PDCD1 domain with an affinity of 1-50 nM.

Datasheet MSDS COA
Specific Inquiry 
Size
5’ Modification
 
3’ Modification
 
Add To
Online Inquiry

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number

TOP
Summary

Specifications
Target Category Protein
Target PDCD1
Alternative Names PD1; Programmed Cell Death 1; CD279; HSLE1; PD-1; Systemic Lupus Erythematosus Susceptibility 2; Programmed Cell Death Protein 1; Protein PD-1; SLEB2; HPD-1; Programmed Cell Death 1 Protein; CD279 Antigen; HPD-L
Gene ID 5133
UniProt ID Q15116
Target Overview Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity.
Type DNA
Species Reactivity Human
Length <50 nt
Affinity (Kd) 1-50 nM
Binding Conditions/Buffer PBS-T with 1 μg/ml BSA and 0.1 μg/ml tRNA
GC Content 55.56%
Molecular Weight 13644.9 g/mole
nmoles/OD260 1.989
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
Online Inquiry
×