Anti-Human PDGFA Aptamer(Cat#: CTMM-0124-RJ49)

This product is an aptamer which binds to Human PDGFA with an affinity of 1-50 nM.

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Summary
Specifications
Target Category Protein
Target PDGFA
Alternative Names Platelet Derived Growth Factor Subunit A; PDGF1; Platelet-Derived Growth Factor Alpha Polypeptide; PDGF-A; Platelet-Derived Growth Factor Alpha Chain; Platelet-Derived Growth Factor Subunit A; PDGF Subunit A; PDGF A-Chain; Platelet-Derived Growth Factor A-Chain; Platelet-Derived Growth Factor A Chain; PDGF-1; PDGFA
Gene ID 5154
UniProt ID P04085
Target Overview This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit A, which can homodimerize, or alternatively, heterodimerize with the related platelet-derived growth factor subunit B. These proteins bind and activate PDGF receptor tyrosine kinases, which play a role in a wide range of developmental processes. Alternative splicing results in multiple transcript variants.
Type DNA
Species Reactivity Human
Length <50 nt
Affinity (Kd) 1-50 nM
Binding Conditions/Buffer 10 mM Tris-HCl, 150 mM NaCl, 5 mM KCl, pH 7.4
GC Content 92.00%
Molecular Weight 15427.9 g/mole
nmoles/OD260 1.824
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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