Anti-Human Progesterone Receptor Aptamer(Cat#: CTMM-0125-TT1)

This product is an aptamer which binds to the human progesterone receptor with an affinity of>200 nM.

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Specifications
Target Category Protein
Target PGR
Alternative Names PGR, NR3C3, PR, progesterone receptor
Gene ID 5241
UniProt ID P06401
Target Overview This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap.
Type RNA
Species Reactivity Human
Length 50-100 nt
Affinity (Kd) >200 nM
Binding Conditions/Buffer 20 mM Tris-HCl, 500 mM NaCl, pH 8.6
GC Content 62.63%
Molecular Weight 32066.23
Extinction Coefficient 956700
nmoles/OD260 1.04526
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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