Anti-Interleukin 32 (IL-32) Aptamer(Cat#: CTApt-M-1079)

This product is an aptamer which binds to the IL-32 with an affinity of <100 nM.

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Summary

Specifications
Target Category Protein
Target IL-32
Alternative Names Interleukin 32;TAIF;NK4;TAIFb;TAIFd;Tumor Necrosis Factor Alpha-Inducing Factor;Natural Killer Cell Transcript 4;Natural Killer Cells Protein 4;Interleukin-32;Interleukin-32 Small;Interleukin-32 Theta;Interleukin-32 Eta;IL-32alpha;IL-32delta;IL-32gamma;IL-32beta;TAIFa;TAIFc;IL-32
Gene ID 9235
UniProt ID P24001
Target Overview This gene encodes a member of the cytokine family. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFalpha from macrophage cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Chemical Modification RNA
Length 80-100 nt
Affinity (Kd) <100 nM
Binding Conditions/Buffer Binding Buffer (20 mM sodium phosphate, 500 mM NaCl and 20 mM imidazole (pH 7.4))
Elution Buffer (20 mM sodium phosphate, 500 mM NaCl and 300 mM imidazole (pH 7.4)
At room temperature.
GC Content 0.5111
Molecular Weight 29155.58 g/mole
Extinction Coefficient 905300 L/(mole·cm)
nmoles/OD260 1.10
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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