Anti-LGR5 Aptamer SELEX Service(Cat#: CTApt-789)

This is an aptamer development services to screening aptamers binds to the LGR5 with an affinity of 1nM~1μM.

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Summary
Specifications
Target Category Protein
Target LGR5
Alternative Names Leucine Rich Repeat Containing G Protein-Coupled Receptor 5; Leucine-Rich Repeat-Containing G-Protein Coupled Receptor 5; G-Protein Coupled Receptor HG38; G-Protein Coupled Receptor 49; G-Protein Coupled Receptor 67; GPR49; GPR67; HG38; FEX; Orphan G Protein-Coupled Receptor HG38; G Protein-Coupled Receptor 49; GRP49; LGR5;
Gene ID 8549
UniProt ID O75473
Target Overview The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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