Anti-M. tuberculosis strain H37Ra Aptamer(Cat#: CTMM-0124-TT1)
This product is an aptamer which binds to the M. tuberculosis strain H37Ra with an affinity of 1-50 nM.
Specific Inquiry 
Specifications
| Target Category |
Cell |
| Target |
M. tuberculosis strain H37Ra |
| Target Overview |
The highly attenuated H37Ra (and the already sequenced virulent H37Rv) strains of M. tuberculosis were derived by serial passaging of the H37 clinical isolate through laboratory media. The genetic basis for the avirulent phenotype of M. tuberculosis H37Ra in animal models is not known. Since the H37Ra strain does not revert to a virulent phenotype on passaging through animals, it is likely that the former has acquired multiple point mutations or small deletions/rearrangements in genes crucial for virulence. |
| Type |
DNA |
| Species Reactivity |
Bacteria |
| Length |
<50 nt |
| Affinity (Kd) |
1-50 nM |
| Binding Conditions/Buffer |
20 mM HEPES, 120 mM KCl, 1 mM CaCl₂, 1 mM MgCl₂, pH 7.4 |
| GC Content |
52.50% |
| Molecular Weight |
12248.97 g/mole |
| nmoles/OD260 |
2.88 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
