This product is an aptamer which binds to the PCB77 with an affinity of <10 µM.
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| Target Category | Small Organic |
| Target | PCB77 |
| Alternative Names | 3,3',4,4'-Tetrachlorobiphenyl; 32598-13-3 |
| Target Overview | PCB 77 belongs to the toxicologically relevant group of dioxin-like PCBs (DL-PCBs, also known as WHO-PCBs) that have molecular-biological properties resembling those of dioxins and furans. |
| Chemical Modification | DNA |
| Length | 20-40 nt |
| Affinity (Kd) | <10 µM |
| Binding Conditions/Buffer | 100 mM NaCl, 20 mM Tris-HCl [pH 7.6], 2 mM MgCl2, 5 mM KCl, 1 mM CaCl22, and 0.02% Tween 20. |
| GC Content | 55.26 |
| Molecular Weight | 11783.7 g/mole |
| Extinction Coefficient | 374200 L/(mole·cm) |
| nmoles/OD260 | 2.67 |