This product is an aptamer which binds to the Phorate with an affinity of <10 µM.
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| Target Category | Small Organic |
| Target | Phorate |
| Target Overview | Phorate, generically, a powerful pesticide effective against insects, mites, and nematodes. It is a systemic insecticide that acts by inhibiting cholinesterases, enzymes involved in transmitting nerve impulses. Chemically, it is an organophosphate, O,O-diethyl S-(ethylthio)methyl phosphorodithioate. |
| Chemical Modification | DNA |
| Length | 40-60 nt |
| Affinity (Kd) | <10 µM |
| Binding Conditions/Buffer | 300mM NaCl, 50 mM KCl, 10 mM MgCl2, 50 mM Tris/HCl, and pH 8.3. |
| GC Content | 0.463 |
| Molecular Weight | 16675.9 g/mole |
| Extinction Coefficient | 517600 L/(mole·cm) |
| nmoles/OD260 | 1.93 |