This is an aptamer development services to screening aptamers binds to the PTX3 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | PTX3 |
| Alternative Names | Pentraxin; TSG-14 2; Tumor Necrosis Factor-Inducible Gene 14 Protein; Tumor Necrosis Factor Alpha-Induced Protein;Pentraxin-Related Protein PTX3; TNF Alpha-Induced Protein 5; Long Pentraxin;TNFAIP5;Pentraxin-Related Gene, Rapidly Induced By IL-1 Beta;Pentaxin-Related Gene, Rapidly Induced By IL-1 Beta;Tumor Necrosis Factor, Alpha-Induced Protein;Tumor Necrosis Factor-Inducible Protein TSG-14;Pentaxin-Related Protein PTX3;Pentraxin 3, Long;TSG14;PTX3 |
| Gene ID | 5806 |
| UniProt ID | P26022 |
| Target Overview | This gene encodes a member of the pentraxin protein family. The expression of this protein is induced by inflammatory cytokines in response to inflammatory stimuli in several mesenchymal and epithelial cell types, particularly endothelial cells and mononuclear phagocytes. The protein promotes fibrocyte differentiation and is involved in regulating inflammation and complement activation. It also plays a role in angiogenesis and tissue remodeling. The protein serves as a biomarker for several inflammatory conditions. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |