This is an aptamer development services to screening aptamers binds to the SEMG2 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | SEMG2 |
| Alternative Names | Semenogelin 2; Semenogelin II; SGII; Semenogelin-2; SEMG2 |
| Gene ID | 6407 |
| UniProt ID | Q02383 |
| Target Overview | The secreted protein encoded by this gene is involved in the formation of a gel matrix that encases ejaculated spermatozoa. Proteolysis by the prostate-specific antigen (PSA) breaks down the gel matrix and allows the spermatozoa to move more freely. The encoded protein is found in lesser abundance than a similar semenogelin protein. An antibacterial activity has been found for a antimicrobial peptide isolated from this protein. The genes encoding these two semenogelin proteins are found in a cluster on chromosome 20. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |