This is an aptamer development services to screening aptamers binds to the THBD with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | THBD |
| Alternative Names | Thrombomodulin; CD141 Antigen; Fetomodulin; CD141; THRM; TM; THPH12; AHUS6; BDCA3; THBD |
| Gene ID | 7056 |
| UniProt ID | P07204 |
| Target Overview | The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |