Name: Recombinant Anti-albumin x Anti-TNF sdAb Bispecific Antibody (IgG-sdAb)
SKU: IGVHH-002
Rating: 5 (1 reviews)

Recombinant Anti-albumin x Anti-TNF Bispecific Antibody (IgG-sdAb) is designed to be expressed as a LC and an extended HC with a sdAb linked to the C terminus. It is a symmetric bispecific and tetravalent molecule, bivalent for each antigen specificity, 2+2 antigen-binding valency. This BsAb can act as PK-modulated ligand antagonist. It is designed for the research of Lupus and rheumatoid arthritis therapy. As required, the sdAb can also be fused to the C terminus of the LC.

Datasheet INQUIRY

Specifications

Targets

albumin & TNF

Type

IgG-sdAb

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Systemic lupus erythematosus (SLE); Rheumatoid arthritis (RA)

Host Animal 1

Mouse

Host Animal 2

llama

Targets

Target 1

albumin

Gene ID

213

UniProt ID

P02768

Alternative Names

ALB; albumin; HAS; PRO0883; PRO0903; PRO1341

Target 2

TNF

Gene ID

7124

UniProt ID

P01375

Alternative Names

TNF; tumor necrosis factor; DIF; TNFA; TNFSF2; TNF-alpha; TNFα; cachectin; APC1 protein; TNF, monocyte-derived; TNF-α; TNF, macrophage-derived; tumor necrosis factor-alpha; tumor necrosis factor ligand superfamily member 2

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-albumin x Anti-TNF sdAb Bispecific Antibody (IgG-sdAb) (CAT#: IGVHH-002)

Specifications

Targets

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