Name: Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (scFv-IgG)
SKU: BSSG-007
Rating: 5 (1 reviews)

Recombinant Anti-albumin x Anti-TNF Bispecific Antibody (scFv-IgG) is formed by an IgG and two scFv fragments. The scFvs from an anti-albumin antibody variable domain are respectively connected to the N terminus of the anti-TNF IgG heavy chains or light chains to form scFv-(H)IgG or scFv-(L)IgG. It is a type of appended IgGs and has 2+2 antigen-binding valency. This BsAb can act as PK-modulated ligand antagonist. It is designed for the research of Lupus and rheumatoid arthritis therapy.

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Specifications

Targets

Albumin & TNF

Type

Appended IgGs

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Systemic lupus erythematosus (SLE); Rheumatoid arthritis (RA)

Targets

Target 1

Albumin

Gene ID

213

UniProt ID

P02768

Alternative Names

ALB; albumin; HAS; PRO0883; PRO0903; PRO1341

Target 2

TNF

Gene ID

7124

UniProt ID

P01375

Alternative Names

TNF; tumor necrosis factor; DIF; TNFA; TNFSF2; TNF-alpha; TNFα; cachectin; APC1 protein; TNF, monocyte-derived; TNF-α; TNF, macrophage-derived; tumor necrosis factor-alpha; tumor necrosis factor ligand superfamily member 2

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (scFv-IgG) (CAT#: BSSG-007)

Specifications

Targets

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