Home > Products > IL12 & IL18 > Recombinant Anti-IL12 x Anti-IL18 Bispecific Antibody (Fab-IgG)

Recombinant Anti-IL12 x Anti-IL18 Bispecific Antibody (Fab-IgG)  (FABIG-171)

Recombinant Anti-IL12 x Anti-IL18 Bispecific Antibody (Fab-IgG) is designed to be expressed as three chains, assembling in vivo and resulting in the construct of Fab-IgG (Tandem Fab-Fc). Fab-IgG has standard Fab and Fc domains, with no mutations, which may permit it has similar affinity binding and PK profile comparable to the parental antibodies. This BsAb can bind and inactivate two ligands simultaneously. It is designed for the research of Arthritis therapy.

Specifications
Targets
IL12 & IL18
Type
Fab-IgG
Species Reactivity
Human
Target 1
IL12
Host Animal 1
Mouse
Target 2
IL18
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Arthritis
Targets
Target 1
IL12
Gene ID
UniProt ID
Alternative Names
P35; CLMF; NFSK; NKSF1; IL-12A; IL12; IL-12; interleukin 12A
Target 2
IL18
Gene ID
UniProt ID
Alternative Names
IGIF; IL-18; IL-1g; IL1F4; interleukin 18; IL18
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