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gp40 Bispecific Antibodies
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CAT# Product Name Species Reactivity BsAb Type Target 1 Host Animal 1 Target 2 Host Animal 2 INQUIRY
T-BSDB-164 Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (Tandem Diabody) Human Tandem Diabody gp40 Mouse TFRC Mouse Inquiry
SCIGG-164 Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (scIgG) Human Single chain IgGs gp40 Mouse TFRC Mouse Inquiry
FVTIG-164 Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (scFv4-Ig) Human scFv4-Ig gp40 Mouse TFRC Mouse Inquiry
BSSG-164 Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (scFv-IgG) Human scFv-IgG gp40 Mouse TFRC Mouse Inquiry
IGLFV-164 Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (IgG(L)-scFv) Human IgG-scFv gp40 Mouse TFRC Mouse Inquiry
BSGV-164 Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (IgG-Fv) Human IgG-Fv gp40 Mouse TFRC Mouse Inquiry
BSDG-164 Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (Fv-IgG) Human Fv-IgG gp40 Mouse TFRC Mouse Inquiry
BABFV-164 Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 gp40 Mouse TFRC Mouse Inquiry
FABVC-164 Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc gp40 Mouse TFRC Mouse Inquiry
SCDBC-164 Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 gp40 Mouse TFRC Mouse Inquiry
BSDBC-164 Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 gp40 Mouse TFRC Mouse Inquiry
SCDBF-164 Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc gp40 Mouse TFRC Mouse Inquiry
BSFVF-164 Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc gp40 Mouse TFRC Mouse Inquiry
BSDBF-164 Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (Diabody-Fc) Human Diabody-Fc gp40 Mouse TFRC Mouse Inquiry
BSTF-164 Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv gp40 Mouse TFRC Mouse Inquiry
BSCFV-164 Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (scFv-Fc) Human scFv-Fc gp40 Mouse TFRC Mouse Inquiry
MNAB-164 Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (Miniantibody) Human Miniantibody gp40 Mouse TFRC Mouse Inquiry
BSFC-164 Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (scFv-CH3) Human scFv-CH3 gp40 Mouse TFRC Mouse Inquiry
BSCC-164 Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL gp40 Mouse TFRC Mouse Inquiry
BIBD-164 Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (Bibody) Human Bibody gp40 Mouse TFRC Mouse Inquiry
FABFV-164 Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (Fab-Fv) Human Fab-Fv gp40 Mouse TFRC Mouse Inquiry
MiniB-164 Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (Minibody) Human Minibody gp40 Mouse TFRC Mouse Inquiry
BSFAB-SAR030 Recombinant Human Anti-gp40 x Human Anti-TFRC Tandem Fab-SAR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin gp40 Human TFRC Human Inquiry
BSFAB-SAR012 Recombinant Anti-gp40 x Anti-TFRC Tandem Fab-SAR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin gp40 Mouse TFRC Mouse Inquiry
BSFAB-NGB030 Recombinant Human Anti-gp40 x Human Anti-TFRC Tandem Fab-NGB immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin gp40 Human TFRC Human Inquiry
BSFAB-NGB012 Recombinant Anti-gp40 x Anti-TFRC Tandem Fab-NGB immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin gp40 Mouse TFRC Mouse Inquiry
BSFAB-MEL030 Recombinant Human Anti-gp40 x Human Anti-TFRC Tandem Fab-MEL immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin gp40 Human TFRC Human Inquiry
BSFAB-MEL012 Recombinant Anti-gp40 x Anti-TFRC Tandem Fab-MEL immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin gp40 Mouse TFRC Mouse Inquiry
BSFAB-BGN030 Recombinant Human Anti-gp40 x Human Anti-TFRC Tandem Fab-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin gp40 Human TFRC Human Inquiry
BSFAB-BGN012 Recombinant Anti-gp40 x Anti-TFRC Tandem Fab-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin gp40 Mouse TFRC Mouse Inquiry
BSFAB-ABR030 Recombinant Human Anti-gp40 x Human Anti-TFRC Tandem Fab-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin gp40 Human TFRC Human Inquiry
BSFAB-ABR012 Recombinant Anti-gp40 x Anti-TFRC Tandem Fab-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin gp40 Mouse TFRC Mouse Inquiry
BSFAB-PAP030 Recombinant Human Anti-gp40 x Human Anti-TFRC Tandem Fab-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin gp40 Human TFRC Human Inquiry
BSFAB-PAP012 Recombinant Anti-gp40 x Anti-TFRC Tandem Fab-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin gp40 Mouse TFRC Mouse Inquiry
BSFAB-SAP030 Recombinant Human Anti-gp40 x Human Anti-TFRC Tandem Fab-SAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin gp40 Human TFRC Human Inquiry
BSFAB-SAP012 Recombinant Anti-gp40 x Anti-TFRC Tandem Fab-SAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin gp40 Mouse TFRC Mouse Inquiry
BSFAB-RTA030 Recombinant Human Anti-gp40 x Human Anti-TFRC Tandem Fab-RTA immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin gp40 Human TFRC Human Inquiry
BSFAB-RTA012 Recombinant Anti-gp40 x Anti-TFRC Tandem Fab-RTA immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin gp40 Mouse TFRC Mouse Inquiry
BSFAB-GEL030 Recombinant Human Anti-gp40 x Human Anti-TFRC Tandem Fab-Gel immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin gp40 Human TFRC Human Inquiry
BSFAB-GEL012 Recombinant Anti-gp40 x Anti-TFRC Tandem Fab-Gel immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin gp40 Mouse TFRC Mouse Inquiry
BSFAB-PE030 Recombinant Human Anti-gp40 x Human Anti-TFRC Tandem Fab-PE immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin gp40 Human TFRC Human Inquiry
BSFAB-PE012 Recombinant Anti-gp40 x Anti-TFRC Tandem Fab-PE immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin gp40 Mouse TFRC Mouse Inquiry
BSFAB-DT030 Recombinant Human Anti-gp40 x Human Anti-TFRC Tandem Fab-DT immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin gp40 Human TFRC Human Inquiry
BSFAB-DT012 Recombinant Anti-gp40 x Anti-TFRC Tandem Fab-DT immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin gp40 Mouse TFRC Mouse Inquiry
BSFV-SAR030 Recombinant Human Anti-gp40 x Human Anti-TFRC Tandem scFv-SAR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin gp40 Human TFRC Human Inquiry
BSFV-SAR012 Recombinant Anti-gp40 x Anti-TFRC Tandem scFv-SAR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin gp40 Mouse TFRC Mouse Inquiry
BSFV-NGB030 Recombinant Human Anti-gp40 x Human Anti-TFRC Tandem scFv-NGB immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin gp40 Human TFRC Human Inquiry
BSFV-NGB012 Recombinant Anti-gp40 x Anti-TFRC Tandem scFv-NGB immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin gp40 Mouse TFRC Mouse Inquiry
BSFV-MEL030 Recombinant Human Anti-gp40 x Human Anti-TFRC Tandem scFv-MEL immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin gp40 Human TFRC Human Inquiry
BSFV-MEL012 Recombinant Anti-gp40 x Anti-TFRC Tandem scFv-MEL immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin gp40 Mouse TFRC Mouse Inquiry
BSFV-BGN030 Recombinant Human Anti-gp40 x Human Anti-TFRC Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin gp40 Human TFRC Human Inquiry
BSFV-BGN012 Recombinant Anti-gp40 x Anti-TFRC Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin gp40 Mouse TFRC Mouse Inquiry
BSFV-ABR030 Recombinant Human Anti-gp40 x Human Anti-TFRC Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin gp40 Human TFRC Human Inquiry
BSFV-ABR012 Recombinant Anti-gp40 x Anti-TFRC Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin gp40 Mouse TFRC Mouse Inquiry
BSFV-PAP030 Recombinant Human Anti-gp40 x Human Anti-TFRC Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin gp40 Human TFRC Human Inquiry
BSFV-PAP012 Recombinant Anti-gp40 x Anti-TFRC Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin gp40 Mouse TFRC Mouse Inquiry
SCDB-164 Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody gp40 Mouse TFRC Mouse Inquiry
FABIG-164 Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (Fab-IgG) Human Fab-IgG gp40 Mouse TFRC Mouse Inquiry
TRIB-164 Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv gp40 Mouse TFRC Mouse Inquiry
BSIG-164 Anti-gp40 x Anti-TFRC Bispecific Antibody (IgG-IgG) Human IgG-IgG gp40 Mouse TFRC Mouse Inquiry
CROSSAB-164 Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (CrossMab) Human CrossMab gp40 Mouse TFRC Mouse Inquiry
IGFV-164 Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (IgG-scFv) Human IgG-scFv gp40 Mouse TFRC Mouse Inquiry
BSDB-164 Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (Diabody) Human Diabody gp40 Mouse TFRC Mouse Inquiry
BSFAB-164 Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (Tandem Fab) Human Tandem Fab gp40 Mouse TFRC Mouse Inquiry
BSFV-164 Recombinant Anti-gp40 x Anti-TFRC Bispecific Antibody (Tandem scFv) Human Tandem scFv gp40 Mouse TFRC Mouse Inquiry

Background

gp40, also known as PDPN, encodes a mucin-type protein with a mass ranging from 36 to 43 kDa. This type-I integral membrane glycoprotein exhibits diverse distribution in various human tissues, gp40's mucin-type character contributes to its physiological function. It is commonly utilized as a marker in fibroblastic reticular cells, lymphatic endothelial cells of lymphoid organs, and lymphatics in the tumor microenvironment and skin. Notably, gp40 might be a potential marker of lung injury, with documented functions in lymphatic endothelial cells, lung alveolar cells, and kidneys. Recent research indicates the involvement of gp40 in immune biology activities of T cells and dendritic cells. The CLEC-2-mediated interaction induces enhanced motility in dendritic cells and aggregation with activation of platelets through PDPN engagement.

Interplay of PDPN/gp40 with intracellular and transmembrane proteins regulates cell migration and adhesion. (Astarita, et al., 2012) Fig.1 Interplay of PDPN/gp40 with intracellular and transmembrane proteins regulates cell migration and adhesion.1

Reference

  1. Astarita, Jillian L., Sophie E. Acton, and Shannon J. Turley. "Podoplanin: emerging functions in development, the immune system, and cancer." Frontiers in immunology 3 (2012): 283.
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