This is an aptamer development services to screening aptamers binds to the ANG with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ANG |
| Alternative Names | Angiogenin; RNASE5; Angiogenin, Ribonuclease, RNase A Family, 5; Ribonuclease A Family Member 5; Ribonuclease 5; RNase 5; RAA1; Epididymis Luminal Protein 168; Ribonuclease A A1; EC 3.1.27.-; EC 3.1.27; HEL168; RNASE4; ALS9; ANG |
| Gene ID | 283 |
| UniProt ID | P03950 |
| Target Overview | The protein encoded by this gene is an exceedingly potent mediator of new blood vessel formation. It hydrolyzes cellular tRNAs resulting in decreased protein synthesis and is similar to pancreatic ribonuclease. In addition, the mature peptide has antimicrobial activity against some bacteria and fungi, including S. pneumoniae and C. albicans. Alternative splicing results in two transcript variants encoding the same protein. This gene and the gene that encodes ribonuclease, RNase A family, 4 share promoters and 5' exons. Each gene splices to a unique downstream exon that contains its complete coding region. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |