Complement C1 Peptide Inhibitor-PIC1 is a highly potent C1 inhibitor which can inhibit ~90% complement activity in a hemolytic assay at Conc. 0.77mM. This inhibitor specifically inhibits the classical and lectin pathways of complement by binding to C1q, it also can bound to the lectin pathway initiator molecule MBL as well as the ficolins H, M and L.
Purity | 0.95 |
Solubility | Soluble in water |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Target | C1q |
Introduction | The complement component 1q (C1q) is a protein complex involved in the complement system, which is also a subunit of the first complement component C1. When C1q binds antigen-antibody complexes, the C1 complex becomes activated. Activation of the C1 complex initiates the classical complement pathway of the complement system. |