Complement C5-IN-1(Cat#: CTI-006)
This product is a potent C5 inhibitor, it interacts with C5 to prevent its cleavage by the C5 convertase and blocks zymosan-induced the membrane-attack complex (MAC) deposition in 50% human whole blood with an IC50 of 0.77 µM.
Summary
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Specifications
| CAS No. |
2365402-67-9 |
| Formula |
C₂₄H₃₂N₂O₆ |
| Molecular Weight |
444.52 |
| SMILES |
COC1=C(OCCCC(C)C)C=C(NC(N[C@H](C2=C(OC)C=CC=C2)C)=O)C(C(O)=O)=C1 |
| IC50 |
IC50: 0.77 µm |
| Purity |
95% |
| Storage |
Store at -4°C for short term; at -20 °C for long-term storage. |
| Target |
C5 |
| Introduction |
The complement component C5 is an effective therapeutic target to discount the activation of complement and prevent functional cells lysis in certain disorders. C5 is cleaved into fragments of C5a and C5b by C5 convertase. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
