This product is an ELISA kit for the determination of Human Complement C5AR1 in the samples of Serum, Plasma, Tissue Homogenate, Cell Lysate. It is highly sensitive and available for the detection of Human Complement C5AR1 as low as 123 pg/mL.
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| Assay Type | Sandwich ELISA |
| Sensitivity | 123 pg/mL (312-20000 pg/mL) |
| Pack Size | 96 tests |
| Species Reactivity | Human |
| Target | C5aR1 |
| Cross Reactivity | No significant cross-reactions have been observed between Human Complement C5AR1 and analogues, but existing techniques may limit the detection of cross-reactions with untested analogues. |
| Applications | ELISA |
| Storage | Short-term storage at 4°C and long-term storage at -20°C. |
| Introduction | C5a anaphylatoxin chemotactic receptor 1 is the receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production. |