Human Complement Factor D ELISA Kit-CTK-469(Cat#: CTK-469)
This product is an ELISA kit for the determination of Human Complement Factor D in the samples of Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate. It is highly sensitive and available for the detection of Human Complement Factor D as low as 0.078 ng/ml.
Summary
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Specifications
| Assay Type |
Sandwich ELISA |
| Sensitivity |
0.078 ng/ml (0.312-20 ng/ml) |
| Pack Size |
96 tests |
| Species Reactivity |
Human |
| Target |
Factor D |
| Cross Reactivity |
No significant cross-reactions have been observed between Human Complement Factor D and analogues, but existing techniques may limit the detection of cross-reactions with untested analogues. |
| Applications |
ELISA |
| Storage |
4°C |
Information
| Introduction |
Complement factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. It also involves in selective cleavage of Arg-|-Lys bond in complement factor B when in complex with complement subcomponent C3b or with cobra venom factor. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
