This product is a HRP conjugated anti-Human Complement CD11b Monoclonal antibody (TJL-169) generated from the Mouse. The antibody can be used for WB, IHC, ELISA.
Clonality | Monoclonal |
Clone | TJL-169 |
Host Animal | Mouse |
Isotype | IgG1 Kappa |
Species Reactivity | Human |
Applications | WB; IHC; ELISA |
Application Notes | WB: 1:100-1:1000 IHC: 1:50-1:500 ELISA: 1:30-1:3000 |
Specificity | This antibody reacts with Human Complement CD11b. |
Purity | ≥95% as determined by SDS-PAGE |
Conjugation | HRP |
Format | Liquid |
Size | 200 µg |
Storage | Store in dark at 4°C. Do Not Freeze. |
Type | Primary Antibody |
Target Name | CD11b |
Alternative Names | CD11 antigen-like family member B; CR-3 alpha chain; Cell surface glycoprotein MAC-1 subunit alpha; leukocyte adhesion receptor MO1; Neutrophil adherence receptor; CD11b; complement receptor 3 |
Gene ID | 3684 |
UniProt ID | P11236 |
Introduction | The Integrin alpha M subunit, also known as MAC-1 alpha subunit or CD11b, combines with the Integrin beta 2 subunit (CD18) to form the non-covalent heterodimer Integrin alpha M/ beta 2, also known as MAC-1 and complement receptor type 3 (CR3). Integrin alpha M/ beta 2 is expressed on granulocytes, macrophages, dendritic cells and natural killer cells. Upon activation, alpha M/ beta 2 can bind several ligands (including ICAM-1, fibrinogen, and the C3 complement fragment, C3bi) to mediate phagocyte adhesion, migRation and ingestion of complement-opsonized particles |