Mouse Anti-Human CD11b Monoclonal Antibody (TJL-171) [PE](Cat#: CTMM-0322-JL1739)

Name: Mouse Anti-Human CD11b Monoclonal Antibody (TJL-171) [PE]
SKU: CTMM-0322-JL1739
Rating: 5 (1 reviews)

This product is a PE conjugated anti-Human Complement CD11b Monoclonal antibody (TJL-171) generated from the Mouse. The antibody can be used for IF, IHC, FCM.

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Specifications

Clonality	Monoclonal
Clone	TJL-171
Host Animal	Mouse
Isotype	IgG1 Kappa
Immunogen	Purified C3bi receptor
Species Reactivity	Human
Applications	IF; IHC; FCM
Application Notes	The optimal working dilutions should be determined by the end user.
Specificity	This antibody reacts with Human Complement CD11b.
Purity	≥95% as determined by SDS-PAGE
Conjugation	PE
Format	Liquid
Size	200 µg
Storage	Store in dark at 4°C. Do Not Freeze.
Type	Primary Antibody

Target

Target Name	CD11b
Alternative Names	CD11 antigen-like family member B; CR-3 alpha chain; Cell surface glycoprotein MAC-1 subunit alpha; leukocyte adhesion receptor MO1; Neutrophil adherence receptor; CD11b; complement receptor 3
Gene ID	3684
UniProt ID	P11240

Information

Introduction

The Integrin alpha M subunit, also known as MAC-1 alpha subunit or CD11b, combines with the Integrin beta 2 subunit (CD18) to form the non-covalent heterodimer Integrin alpha M/ beta 2, also known as MAC-1 and complement receptor type 3 (CR3). Integrin alpha M/ beta 2 is expressed on granulocytes, macrophages, dendritic cells and natural killer cells. Upon activation, alpha M/ beta 2 can bind several ligands (including ICAM-1, fibrinogen, and the C3 complement fragment, C3bi) to mediate phagocyte adhesion, migRation and ingestion of complement-opsonized particles

For Research Use Only. Not for Diagnostic or Therapeutic Applications.