This product is an iFluor® 488 conjugated anti-Human Complement CD59 Monoclonal antibody (TJL-123) generated from the Mouse. The antibody can be used for Flow, ICC/IF, IHC, IHC-P.
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| Clonality | Monoclonal |
| Clone | TJL-123 |
| Host Animal | Mouse |
| Isotype | IgG1 Kappa |
| Immunogen | Recombinant full-length Human CD59 protein |
| Species Reactivity | Human |
| Applications | Flow; ICC/IF; IHC; IHC-P |
| Application Notes | The optimal working dilutions should be determined by the end user. |
| Specificity | This antibody reacts with Human Complement CD59. |
| Conjugation | iFluor® 488 |
| Format | Liquid |
| Size | 0.1 ml |
| Storage | Store in dark at 4°C. Do Not Freeze. |
| Type | Primary Antibody |
| Target Name | CD59 |
| Alternative Names | CD59 Molecule; CD59 Molecule, Complement Regulatory Protein; Membrane Attack Complex Inhibition Factor; 20 KDa Homologous Restriction Factor; Membrane Inhibitor Of Reactive Lysis; CD59 Glycoprotein; MEM43 Antigen; MAC-IP; CD59; MAC-Inhibitory Protein; CD59 Antigen, Complement Regulatory Protein; MAC-Inhibitory Protein; Protectin |
| Gene ID | 966 |
| UniProt ID | P13987 |
| Introduction | Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorpoRation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. |