Mouse Anti-Human Complement C5a/C5a des Arg Monoclonal Antibody (CTJS-723)(Cat#: CTA-528)
This product is an anti-Human Complement C5a/C5a des Arg Monoclonal antibody (CTJS-723) generated from the Mouse. The antibody can be used for WB; ELISA; IHC; Funcs.
Summary
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Specifications
| Clonality |
Monoclonal |
| Clone |
CTJS-723 |
| Host Animal |
Mouse |
| Isotype |
IgG2a |
| Immunogen |
Recombinant C5a. The exact sequence is proprietary. |
| Species Reactivity |
Human |
| Applications |
WB; ELISA; IHC; Funcs |
| Application Notes |
WB: 1:50
IHC: 1:50
ELISA: 1:50
The optimal working dilutions should be determined by the end user. |
| Specificity |
This antibody reacts with Human complement C5a/C5a des Arg. |
| Purity |
≥95% as determined by SDS-PAGE |
| Format |
Liquid |
| Size |
100 µg |
| Storage |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
| Type |
Primary Antibody |
Target
| Target Name |
C5a |
| Alternative Names |
Complement C5a; C5a des-Arg; Inactivated C5a |
| Gene ID |
727 |
| UniProt ID |
P01031 |
Information
| Introduction |
Complement C5a, together with C5b, are protein fragments released from cleavage of complement component C5 by protease C5-convertase. C5a is a chemotactic agent, as well as an anaphylatoxin, playing critical roles in migration and adherence of neutrophils and monocytes, smooth muscle contraction, and vascular permeability increase. Once complement C5a is produced, it rapidly metabolised inti C5a desArg by a serum enzyme carboxypeptidase B through removal of the C terminal arginine. Compared with C5a, C5a des-Arg is a much less potent anaphylatoxin that alsi induces C5a biological activities. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
