This product is an unconjugated anti-Human Complement C7 Monoclonal antibody (CTJS-753) generated from the Mouse. The antibody can be used for WB; ELISA.
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| Clonality | Monoclonal |
| Clone | CTJS-753 |
| Host Animal | Mouse |
| Isotype | IgG |
| Immunogen | Purified human C7 |
| Species Reactivity | Human |
| Applications | WB; ELISA |
| Application Notes | WB: 1:100-1:2000 ELISA: 1:100-1:2000 The optimal working dilutions should be determined by the end user. |
| Specificity | This antibody reacts with Human complement C7. |
| Purity | ≥95% as determined by SDS-PAGE |
| Format | Liquid |
| Size | 50 µg |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
| Type | Primary Antibody |
| Target Name | C7 |
| Alternative Names | Complement C7; Complement Component 7; Complement Component C7 |
| Gene ID | 730 |
| UniProt ID | P10643 |
| Introduction | Complement component 7 is a protein involved in the complement system of the innate immune system. C7 is part of the membrane attack complex (MAC) which creates a hole on pathogen surfaces, leading to cell lysis and death. Its primary task is to bind the C5bC6 complex together. This junction alters the configuration of the protein molecules, exposing a hydrophobic site on C7 that allows the C7 to insert into the phospholipid bilayer of the pathogen. |