This product is an iFluor® 488 conjugated anti-Human Complement CR1 Monoclonal antibody (TJL-143) generated from the Mouse. The antibody can be used for Flow, ICC/IF, IHC, IHC-P.
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| Clonality | Monoclonal |
| Clone | TJL-143 |
| Host Animal | Mouse |
| Isotype | IgG1 Kappa |
| Immunogen | Human CR1 |
| Species Reactivity | Human |
| Applications | Flow; ICC/IF; IHC; IHC-P |
| Application Notes | The optimal working dilutions should be determined by the end user. |
| Specificity | This antibody reacts with Human Complement CR1. |
| Purity | ≥95% as determined by SDS-PAGE |
| Conjugation | iFluor® 488 |
| Format | Liquid |
| Size | 0.1 ml |
| Storage | Store in dark at 4°C. Do Not Freeze. |
| Type | Primary Antibody |
| Target Name | CR1 |
| Alternative Names | CR1 (CD35): Complement C3b/C4b Receptor 1 (Knops Blood Group); Complement Component (3b/4b) Receptor 1 (Knops Blood Group); C3b/C4b Receptor; CD35 Antigen; C3BR; Complement Component (3b/4b) Receptor 1, Including Knops Blood Group System; Complement Component 3b/4b Receptor 1 (Knops Blood Group); Complement Receptor Type 1; Knops Blood Group Antigen; Complement Receptor 1; C3-Binding Protein; C4BR; KN |
| Gene ID | 1378 |
| UniProt ID | P17927 |
| Introduction | Complement receptor 1 (CR1) also known as CD35, cluster of differentiation 35, is a protein that in humans is encoded by the CR1 gene. CR1 can act as a negative regulator of the complement cascade, mediate immune adherence and phagocytosis and inhibit both the classic and alternative pathways. |