This product is an unconjugated anti-Human Complement CR2 Monoclonal antibody (TJL-157) generated from the Mouse. The antibody can be used for IHC(P), ICC/IF.
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| Clonality | Monoclonal |
| Clone | TJL-157 |
| Host Animal | Mouse |
| Isotype | IgG2b |
| Immunogen | Human CR2, a.a.980-1033 |
| Species Reactivity | Human |
| Applications | IHC(P); ICC/IF |
| Application Notes | IHC(P): 1:100-1:500 ICC/IF: 1:50-1:100 |
| Specificity | This antibody reacts with Human Complement CR2. |
| Purity | ≥95% as determined by SDS-PAGE |
| Conjugation | Unconjugated |
| Format | Liquid |
| Size | 100 µL |
| Storage | Store at 4°C for short term. Store at -20°C for long term. Avoid freeze-thaw cycle. |
| Type | Primary Antibody |
| Target Name | CR2 |
| Alternative Names | Complement C3d Receptor 2; Complement Component (3d/Epstein Barr Virus) Receptor 2; Complement Component 3d Receptor 2; Epstein-Barr Virus Receptor; EBV Receptor; Complement C3d Receptor; CD21 Antigen; Cr2; CR; C3DR; CD21; CVID7; SLEB9 |
| Gene ID | 1380 |
| UniProt ID | P17927 |
| Introduction | omplement receptor type 2 (CR2), also known as complement C3d receptor, Epstein-Barr virus receptor, and CD21 (cluster of differentiation 21), is a protein that in humans is encoded by the CR2 gene. CR2 is involved in the complement system. It binds to iC3b (inactive derivative of C3b), C3dg, or C3d. B cells have CR2 receptors on their surfaces, allowing the complement system to play a role in B-cell activation and matuRation. it is receptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRNPU, and participates in B lymphocytes activation. |