Mouse Anti-Human Ficolin-2 Monoclonal Antibody (TJL-228) [DyLight 755](Cat#: CTMM-0322-JL2370)
This product is a DyLight 755 conjugated anti-Human Complement Ficolin-2 Monoclonal antibody (TJL-228) generated from the Mouse. The antibody can be used for WB, ELISA.
Summary
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Specifications
| Clonality |
Monoclonal |
| Clone |
TJL-228 |
| Host Animal |
Mouse |
| Isotype |
IgG1 Kappa |
| Immunogen |
Recombinant HumanFicolin-2 and full-length L-Ficolin (Ficolin-2) protein |
| Species Reactivity |
Human |
| Applications |
WB; ELISA |
| Application Notes |
ELISA: 1:100-1:2000
WB: 1:100-1:2000
The optimal working dilutions should be determined by the end user. |
| Specificity |
This antibody reacts with Human Complement Ficolin-2. |
| Purity |
≥95% as determined by SDS-PAGE |
| Conjugation |
DyLight 755 |
| Format |
Liquid |
| Size |
0.1 ml |
| Storage |
Store in dark at 4°C. Do Not Freeze. |
| Type |
Primary Antibody |
Target
| Target Name |
Ficolin-2 |
| Alternative Names |
Ficolin; Collagen/Fibrinogen Domain-Containing Protein 2; Serum Lectin P35; L-Ficolin; 37 KDa Elastin-Binding Protein; Ficolin-Beta; Ficolin-2; Ficolin B; Hucolin; EBP-37; FCNL; Ficolin (Collagen/Fibrinogen Domain Containing Lectin) 2 (Hucolin); Ficolin-B; P35 |
| Gene ID |
2220 |
| UniProt ID |
Q15485 |
Information
| Introduction |
Ficolin-2 is a protein that in humans is encoded by the FCN2 gene, which is initially identified as L-ficolin. L-Ficolin is an innate immunity pattern recognition molecule found in human serum. It binds to distinct pathogen-associated molecular patterns (PAMP) such as carbohydRates (GlcNAc), lipoteichoic acid and acetylated groups, thereby facilitating phagocytosis and activation of complement through the lectin route using the same serine proteases as mannose-binding lectin (MBL) named MASP (MBL-associated serine protease). |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
