Mouse CD59a ELISA Kit-CTK-721(Cat#: CTK-721)

This product is an ELISA kit for the determination of Mouse CD59a in the samples of Plasma and Serum. It is highly sensitive and available for the detection of Mouse CD59a as low as 25.5 pg/mL.

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Specifications
Assay Type Sandwich ELISA
Sensitivity 25.5 pg/mL (62.50-4000 pg/mL)
Pack Size 96 tests
Species Reactivity Mouse
Target CD59a
Cross Reactivity No significant cross-reactions have been observed between Mouse CD59a and analogues, but existing techniques may limit the detection of cross-reactions with untested analogues.
Applications ELISA
Storage The storage of components varies. Please refer to the instructions for details.
Information
Introduction CD59 glycoprotein is a potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes.
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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