This product is a 10.25 kDa native human C5a desArg protein isolated from normal human serum. It is availible for Functional Assays, ELISA.
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| Specie Reactivity | Human |
| Target | C5a desArg |
| Molecule Mass | 10.25 kDa |
| Purity | >97% determined by SDS-PAGE |
| Endotoxin | <1.0EU per 1µg (determined by the LAL method) |
| Formulation | 20 mM HEPES, 100 mM NaCl, pH 7.2 |
| Applications | Functional Assays; ELISA |
| Product Form | Frozen liquid |
| Storage | Store at -20°C/-80°C. Avoid freeze-thaw cycles. |
| Introduction | Once complement C5a is produced, it rapidly metabolised inti C5a desArg by a serum enzyme carboxypeptidase B through removal of the C terminal arginine. Compared with C5a, C5a des-Arg is a much less potent anaphylatoxin that alsi induces C5a biological activities. |
| Alternative Names | C5a des-Arg; Inactivated C5a |