Native Human Complement C5a desArg Protein(Cat#: CTP-269)
This product is a 10.25 kDa native human C5a desArg protein isolated from normal human serum. It is availible for Functional Assays, ELISA.
Summary
Specifications
| Specie Reactivity |
Human |
| Target |
C5a desArg |
| Molecule Mass |
10.25 kDa |
| Purity |
>97% determined by SDS-PAGE |
| Endotoxin |
<1.0EU per 1µg (determined by the LAL method) |
| Formulation |
20 mM HEPES, 100 mM NaCl, pH 7.2 |
| Applications |
Functional Assays; ELISA |
| Product Form |
Frozen liquid |
| Storage |
Store at -20°C/-80°C. Avoid freeze-thaw cycles. |
Protein Information
| Introduction |
Once complement C5a is produced, it rapidly metabolised inti C5a desArg by a serum enzyme carboxypeptidase B through removal of the C terminal arginine. Compared with C5a, C5a des-Arg is a much less potent anaphylatoxin that alsi induces C5a biological activities. |
| Alternative Names |
C5a des-Arg; Inactivated C5a |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
