Native Human Complement C5b-C6 Protein(Cat#: CTP-270)

This product is a 285 kDa native human C5b-C6 protein isolated from normal human serum. It is availible for Functional Assays.

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Summary

Specifications
Specie Reactivity Human
Target C5b-C6
Molecule Mass 285 kDa
Purity >90 % determined by SDS-PAGE
Endotoxin <1.0EU per 1µg (determined by the LAL method)
Formulation 10 mM HEPES, 120 mM NaCl, pH 7.2
Applications Functional Assays
Product Form Frozen liquid
Storage Store at -20°C/-80°C. Avoid freeze-thaw cycles.
Protein Information
Introduction C5b-6 is a stable complex of complement C5b and C6 firstly produced during membrane attack complex (MAC) formation. When C5b was relased from C5 by C5 convertase, it is unstable and binds a single C6 forming C5b-6 before binding to a single C7 molecule. C5b,-6 can be used to lyse cell membrane, virus or particle when adding C7, C8 and C9.
Alternative Names C5b-6; C5b-6 complex
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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