Rat Anti-Mouse C5aR1 Monoclonal Antibody (CTJS-762) [iFluor® 488](Cat#: CTA-945)

Name: Rat Anti-Mouse C5aR1 Monoclonal Antibody (CTJS-762) [iFluor® 488]
SKU: CTA-945
Rating: 5 (1 reviews)

This product is a conjugated anti-Mouse C5aR1 Monoclonal antibody (CTJS-762) generated from the Rat. The antibody can be used for FC.

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Specifications

Clonality	Monoclonal
Clone	CTJS-762
Host Animal	Rat
Isotype	IgG2b κ
Immunogen	RBL-2H3 transfected cells expressing murine C5aR
Species Reactivity	Mouse
Applications	FC
Application Notes	FC: 1.0 µg/10^6 cells The optimal working dilutions should be determined by the end user.
Specificity	This antibody reacts with Mouse C5aR1.
Purity	≥95% as determined by SDS-PAGE
Conjugation	iFluor® 488
Format	Liquid
Size	25; 100 μg
Storage	Store in dark at 4°C. Do Not Freeze.
Type	Primary Antibody

Target

Target Name	C5aR1
Alternative Names	Complement C5a Receptor 1; C5AR; C5a Anaphylatoxin Chemotactic Receptor 1; Complement Component 5a Receptor 1; C5a-R; C5R1; CD88; Complement Component 5 Receptor 1 (C5a Ligand); C5a Anaphylatoxin Chemotactic Receptor 4; Complement Component 5 Receptor 1; C5a Anaphylatoxin Receptor; CD88 Antigen; C5AR1; C5aR
Gene ID	12273
UniProt ID	P30993

Information

Introduction

Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production.

For Research Use Only. Not for Diagnostic or Therapeutic Applications.