Recombinant Human Complement Component C1R Protein-10His tag(Cat#: CTP-021)
This product is a recombinant human Complement Component C1R protein (51 kDa A chain and 28 kDa B chain) with a C-terminal 10-His tag expressed in the mouse myeloma cell line. It is available for Enzyme Activity Assays.
Summary
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Specifications
| Expressed Host |
Mouse myeloma cell line, NS0 |
| Specie Reactivity |
Human |
| Target |
C1R |
| Molecule Mass |
51 kDa (A chain) & 28 kDa (B chain) |
| Purity |
>95% by SDS-PAGE under reducing conditions and visualized by silver stain |
| Endotoxin |
<1.0EU per 1µg (determined by the LAL method) |
| Formulation |
50 mM Tris and 150 mM NaCl, pH 7.5 |
| Applications |
Enzyme Activity Assays |
| Product Form |
Lyophilized |
| Storage |
Store at 2 to 8°C after reconstitution for short term (1-2 weeks). For long term storage, aliquot and store at -20 or -80°C. Avoid repeated freezing and thawing cycles. |
Protein Information
| Introduction |
Complement C1r subcomponent is a protein involved in the complement system of the innate immune system. In humans, C1r is encoded by the C1R gene. C1r along with C1q and C1s form the C1 complex, which is the first component of the serum complement system. C1r is an enzyme that activates C1s to its active form, by proteolytic cleavage. C1r has been shown to interact with C1s. C1r cleaves C1s to form the active form of C1s. |
| Alternative Names |
Complement C1r; Complement Component 1, R Subcomponent; Complement Component 1 Subcomponent R; Complement C1r Subcomponent; EC 3.4.21.41; EDSPD1 |
| Gene ID |
715 |
| UniProt ID |
P00736 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
