Recombinant Human Complement Component C2 Protein-6His tag(Cat#: CTP-037)
This product is a 82 kDa recombinant human Complement Component C2 protein with a C-terminal 6-His tag expressed in the mouse myeloma cell line. It is available for Enzyme Activity Assays.
Summary
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Specifications
| Expressed Host |
Mouse myeloma cell line, NS0 |
| Specie Reactivity |
Human |
| Target |
C2 |
| Molecule Mass |
82 kDa |
| Purity |
>95% by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie Blue Staining |
| Endotoxin |
<1.0EU per 1µg (determined by the LAL method) |
| Formulation |
Tris, NaCl and CaCl2 |
| Applications |
Enzyme Activity Assays |
| Product Form |
Liquid |
| Storage |
Store at -20/-80°C. Aliquot to avoid repeated freezing and thawing. |
Protein Information
| Introduction |
Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase. C2 is a major histocompatibility complex class-III protein. Selective cleavage of Arg-|-Ser bond in complement component C3 alpha-chain to form C3a and C3b, and Arg-|-Xaa bond in complement component C5 alpha-chain to form C5a and C5b. |
| Alternative Names |
Complement C2; Complement Component 2; C3/C5 Convertase; Complement Component C2; EC 3.4.21.43; ARMD14; CO2 |
| Gene ID |
717 |
| UniProt ID |
P06681 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
