Recombinant Human Complement Factor D Protein-His-GST tag(Cat#: CTP-108)
This product is a 59 kDa recombinant human Complement Factor D protein with a N-terminal His and GST tag expressed in the E. coli. It is available for WB, ELISA, IP.
Summary
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Specifications
| Expressed Host |
E. Coli |
| Specie Reactivity |
Human |
| Target |
Factor D |
| Molecule Mass |
59 kDa |
| Purity |
>95% as determined by SDS-PAGE |
| Endotoxin |
<1.0EU per 1µg (determined by the LAL method) |
| Formulation |
PBS, pH 7.4, containing 0.01% SKL, 1 mM DTT, 5% Trehalose and Proclin 300 |
| Applications |
WB; ELISA; IP |
| Product Form |
Lyophilized |
| Storage |
Store at 2 to 8°C after reconstitution for short term (1-2 weeks). For long term storage, aliquot and store at -20 or -80°C. Avoid repeated freezing and thawing cycles. |
Protein Information
| Introduction |
Complement factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. It also involves in selective cleavage of Arg-|-Lys bond in complement factor B when in complex with complement subcomponent C3b or with cobra venom factor. |
| Alternative Names |
Adipsin; AND; ADNcomplement factor D; AMBP-1; C3 convertase activator; CFD; complement factor D (adipsin); complement factor D preproprotein; Complement Factor D; D component of complement (adipsin); DF; PFD; Properdin factor DADIPSIN |
| Gene ID |
1675 |
| UniProt ID |
P00746 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
