This product is a 55.8 kDa recombinant human CRIg protein with a C-terminus Fc region of human IgG1 tag expressed in the mouse myeloma cell line, NS0. It is availible for Functional Assays.
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| Expressed Host | Mouse myeloma cell line, NS0 |
| Specie Reactivity | Human |
| Target | CRIg |
| Molecule Mass | 55.8 kDa |
| Purity | >95 % determined by SDS-PAGE |
| Endotoxin | <1.0EU per 1µg (determined by the LAL method) |
| Formulation | PBS |
| Applications | Functional Assays |
| Product Form | Lyophilized |
| Storage | Store at -20°C/-80°C. Avoid freeze-thaw cycles. |
| Introduction | Phagocytic receptor, strong negative regulator of T-cell proliferation and IL2 production. Potent inhibitor of the alternative complement pathway convertases. |
| Alternative Names | V-Set And Immunoglobulin Domain Containing 4; Z39IG; CRIg; Complement Receptor Of The Immunoglobulin Superfamily; V-Set And Immunoglobulin Domain-Containing Protein 4; Protein Z39Ig; Ig Superfamily Protein; VSIG4 |
| Gene ID | 11326 |
| UniProt ID | Q9Y279 |