This product is a 9 kDa recombinant mouse Complement Component C5a R1 protein expressed in the E. coli. It is available for Bioactivity Assays.
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| Expressed Host | E. Coli |
| Specie Reactivity | Mouse |
| Target | C5aR1 |
| Molecule Mass | 9 kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <1.0EU per 1µg (determined by the LAL method) |
| Formulation | Sterile filtered and lyophilized with no additives. |
| Applications | Bioactivity Assays |
| Product Form | Lyophilized |
| Storage | Store at 2 to 8°C after reconstitution for short term (1-2 weeks). For long term storage, aliquot and store at -20 or -80°C. Avoid repeated freezing and thawing cycles. |
| Introduction | C5a anaphylatoxin chemotactic receptor 1 is the receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production. |
| Alternative Names | C5a anaphylatoxin chemotactic receptor; C5A; C5aR; C5a-R; C5AR1; C5ARC5a anaphylatoxin receptor; C5R1C5a ligand; CD88 antigen; CD88; complement component 5 receptor 1 (C5a ligand); complement component 5 receptor 1; complement component 5a receptor 1; Complement Component C5a R1; Complement Component C5aR1 |
| Gene ID | 12273 |
| UniProt ID | P06684 |