Recombinant Mouse Complement Factor D Protein-10His tag(Cat#: CTP-109)
This product is a 27 kDa recombinant mouse Complement Factor D protein with a C-terminal 10-His tag expressed in the mouse myeloma cell line. It is available for Enzyme Activity Assays.
Summary
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Specifications
| Expressed Host |
Mouse myeloma cell line, NS0 |
| Specie Reactivity |
Mouse |
| Target |
Factor D |
| Molecule Mass |
27 kDa |
| Purity |
>95% by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie Blue Staining |
| Endotoxin |
<1.0EU per 1µg (determined by the LAL method) |
| Formulation |
Tris and NaCl. |
| Applications |
Enzyme Activity Assays |
| Product Form |
Liquid |
| Storage |
Store at -20/-80°C. Aliquot to avoid repeated freezing and thawing. |
Protein Information
| Introduction |
Complement factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. It also involves in selective cleavage of Arg-|-Lys bond in complement factor B when in complex with complement subcomponent C3b or with cobra venom factor. |
| Alternative Names |
Adipsin; AND; ADNcomplement factor D; AMBP-1; C3 convertase activator; CFD; complement factor D (adipsin); complement factor D preproprotein; Complement Factor D; D component of complement (adipsin); DF; PFD; Properdin factor DADIPSIN |
| Gene ID |
11537 |
| UniProt ID |
P03953 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
