This product is a 19.0 kDa recombinant rat Complement 1 Inhibitor with two N-terminal Tags (His-tag and S-tag) expressed in the E. Coli. It is available for WB, ELISA, IP.
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| Expressed Host | E. Coli |
| Specie Reactivity | Rat |
| Target | C1 Inhibitor |
| Molecule Mass | 19.0 kDa |
| Purity | >95% as determined by SDS-PAGE |
| Endotoxin | <1.0EU per 1µg (determined by the LAL method) |
| Formulation | PBS, pH 7.4, containing 5% sucrose, 0.01% sarcosyl |
| Applications | WB; ELISA; IP |
| Product Form | Lyophilized |
| Storage | Store at 2 to 8°C after reconstitution for short term (1-2 weeks). For long term storage, aliquot and store at -20 or -80°C. Avoid repeated freezing and thawing cycles. |
| Introduction | Activation of the C1 complex is under control of the C1-inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein. |
| Alternative Names | Plasma protease C1 inhibitor; C1-IA; C1 Inh; C1 esterase inhibitor; C1-inhibiting factor; Serpin G1 |
| Gene ID | 295703 |
| UniProt ID | Q6P734 |