Hi-Affi™ In Vitro Cell based Adrenergic Receptor Functional Assay Service

Adrenergic Receptors with Prospect

Adrenergic receptors (ARs), or adrenoceptors, are a group of GPCRs distributed throughout every part of the body. They play a vital role in regulating diverse physiological processes in humans. Recent research indicates that therapeutic targeting by modification of the adrenergic system could function as an effective systemic therapy for cancers, particularly bladder cancer. Consequently, comprehending the function of adrenergic receptors has great significance for its application in drug development of cancer therapy.

Adenosine sensor A1AR-A2AAR heteromer schematic Fig.1 Adrenergic receptors-mediated signaling in endothelial and cancer cells.¹

Our Hi-Affi™ In Vitro Cell-based Adrenergic Receptor Functional Assay Service

Creative Biolabs provides rapid and effective Hi-Affi™ in vitro cell-based adrenergic receptor functional assay service to support global customers' diverse needs. Our Hi-Affi™ in vitro cell-based adrenergic receptor functional assay services are conducted by exposing samples to ligands in a concentration gradient and then measuring calcium flux and protein activities of downstream signaling. We provide a wide range of services that include, but are not restricted to, the examination of signaling pathways, which may include the recruitment of adaptor protein and calcium flux-mediated G protein activation. Creative Biolabs is dedicated to presenting the desirable outcomes for global customers.

Adenosine receptor agonists inhibit cAMP production to regulate physiological activity Fig.2 Adrenergic receptor signaling in neuroimmune communication.²

The breadth of Our Hi-Affi™ In Vitro Cell-based Adrenergic Receptor Functional Assay Service

Fig.3 Our service process. (Creative Biolabs Original) Fig.3 The workflow of our Hi-Affi™ in vitro cell-based adrenergic receptor functional assay service.

Multiple types of cell lines: We offer a wide range of stable expressing cell lines for global customers' projects, such as human melanoma A375 cell lines, MCF-7 human breast cancer cells, U87MG human glioblastoma cells, DLD-1 colon carcinoma cells, and others.

Robust experiment systems: We have a well-established experimental system that has been optimized over the course of many years and several projects. We have full confidence that through employing straightforward experimental approaches, we will achieve the anticipated outcomes for worldwide customers.

A competent research team: Our research team is made up of experts with plenty of professional training, practical experience, and knowledge. Along with cutting-edge technologies, which brings us confidence in providing global customers with high-quality data.

Comprehensive customized services: Our Hi-Affi™ in vitro cell-based adrenergic receptor functional assay service is both thorough and customizable. Throughout the procedure from sample collection to final results, we've got you covered with cutting-edge technological solutions to enable your projects' success.

Work with Creative Biolabs

Contact flowchart. (Creative Biolabs Original)

Feel free to get in touch with us if you have any questions concerning our Hi-Affi™ in vitro cell-based adrenergic receptor functional assay service. We are eager to begin collaborating with customers from all over the world.

Frequently Asked Questions

Q1: What is the difference between epinephrine & adrenaline?

A1: Epinephrine functions as both a neurotransmitter and a hormone, however, it is mostly a hormone. Adrenaline, or epinephrine, plays a significant role in the body's fight-or-flight response. It is also used to treat a variety of life-threatening illnesses as a medicine.

References

Xanthopoulos, Athanasios, et al. "A systematic review on the role of adrenergic receptors in angiogenesis regulation in health and disease." International Journal of Translational Medicine 1.3 (2021): 353-365.
Distributed under Open Access License CC BY 4.0. The original image was modified by extracting and regrouping, and the title was changed to “Adrenergic receptors-mediated signaling in endothelial and cancer cells”.
Chhatar, Sushanta, and Girdhari Lal. "Role of adrenergic receptor signaling in neuroimmune communication." Current Research in Immunology 2 (2021): 202-217.
Distributed under Open Access License CC BY 4.0, without modification.