Home > Products > albumin & IL-6R > Recombinant Anti-albumin x Anti-IL-6R Bispecific Antibody (IgG(L)-scFv)

Recombinant Anti-albumin x Anti-IL-6R Bispecific Antibody (IgG(L)-scFv)  (IGLFV-H194)

Recombinant Anti-albumin x Anti-IL-6R Bispecific Antibody (IgG(L)-scFv) is formed by an IgG and two scFv moieties. The scFv fragments from an anti-albumin antibody are fused to the C terminus of an anti-IL-6R IgG light (L) chains, or vice versa. It is a type of appended IgGs, which is bispecific and tetravalent (2+2 antigen-binding valency). This BsAb can act as PK-modulated receptor antagonist. It is designed for the research of Lupus, rheumatoid arthritis therapy.

Specifications
Targets
albumin & IL-6R
Type
Appended IgGs
Species Reactivity
Human
Target 1
albumin
Host Animal 1
Human
Target 2
IL-6R
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Systemic lupus erythematosus (SLE); Rheumatoid arthritis (RA)
Targets
Target 1
albumin
Gene ID
UniProt ID
Alternative Names
ALB; albumin; HAS; PRO0883; PRO0903; PRO1341
Target 2
IL-6R
Gene ID
UniProt ID
Alternative Names
IL6R; IL-6R; interleukin 6 receptor; IL6Q; gp80; CD126; IL6RA; IL6RQ; IL-6RA; IL-6R-1

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